09/25/2015
| Home Team | Home Team Score | Away Team | Away Team Score |
| Albertville | 28 | Boaz Pirates | 17 |
| Appalachian Eagles | 39 | Southeastern School | 0 |
| Arab Knights | 7 | Guntersville Wildcats | 37 |
| Ardmore Tigers | 29 | Clements Colts | 6 |
| Ashville Bulldogs | 0 | Montevallo | 58 |
| Austin | 27 | Huntsville | 20 |
| Beauregard | 48 | Straughn | 0 |
| Brewer Patriots | 3 | Decatur Red Raiders | 27 |
| Briarwood | 0 | Oak Mountain | 35 |
| Brilliant Tigers | 14 | Hackleburg | 46 |
| Buckhorn Bucks | 31 | Johnson Jaguars | 30 |
| Carbon Hill | 28 | Winston County Yellow Jackets | 49 |
| Center Point Eagles | 2 | Parker Thundering Heard | 42 |
| Central Phoenix City High School | 21 | Opelika | 27 |
| Central-Florence | 21 | Haleyville Lions | 48 |
| Chelsea | 40 | Helena High School | 20 |
| Cherokee County Warriors | 28 | Ohatchee Indians | 19 |
| Chilton County | 56 | Marbury High School | 7 |
| Cleveland Panthers | 35 | J.B. Pennington Tigers | 7 |
| Colbert County Indians | 18 | Deshler Tigers | 13 |
| Colbert Heights Wildcats | 50 | Marion County Red Raiders | 14 |
| Columbia Trailblazers | 14 | Lee | 41 |
| Corner | 15 | Oak Grove | 29 |
| Crossville Lions | 7 | Sand Rock Wildcats | 31 |
| Cullman Bearcats | 34 | Fayette County | 6 |
| Douglas Eagles | 27 | Brindlee Mountain Lions | 0 |
| East Limestone Indians | 14 | Athens Golden Eagles | 0 |
| Elmore County | 42 | Reeltown High School | 53 |
| Fairfield Tigers | 13 | Midfield | 0 |
| Falkville Blue Devils | 54 | West Morgan Rebels | 20 |
| Fayetteville | 17 | Donoho Falcons | 9 |
| Florence | 24 | Bob Jones Patriots | 42 |
| Gaylesville Trojans | 6 | Gaston Bulldogs | 40 |
| Geraldine Bulldogs | 27 | Sardis Lions | 20 |
| Glencoe Yellow Jackets | 42 | Hokes Bluff Eagles | 7 |
| Good Hope Raiders | 47 | Curry Yellow Jackets | 6 |
| Goose Creek (SC) | 38 | Gadsden City | 35 |
| Handley | 42 | Lanett | 28 |
| Hartselle Tigers | 38 | Grissom | 13 |
| Hatton Hornets | 20 | East Lawrence Eagles | 22 |
| Hayden Wildcats | 48 | Lawrence County Red Devils | 6 |
| Hazel Green Trojans | 21 | Fort Payne Wildcats | 17 |
| Holly Pond Broncos | 0 | Fairview Aggies | 40 |
| Horseshoe Bend | 14 | Collinsville Panthers | 28 |
| Hueytown Golden Gophers | 27 | Pleasant Grove Spartans | 20 |
| Huffman | 0 | Pell City | 3 |
| Ider Hornets | 9 | North Sand Mountain Bison | 7 |
| Jacksonville Christian Thunder | 35 | Alabama School of Deaf | 12 |
| James Clemens | 51 | Mountain Brook | 14 |
| John Carroll | 17 | Mortimer Jordan Blue Devils | 42 |
| Lafayette | 22 | Wadley | 20 |
| Lauderdale County Tigers | 24 | Brooks Lions | 28 |
| Leeds | 29 | Piedmont | 12 |
| Lexington Golden Bears | 6 | Rogers Pirates | 7 |
| Maplesville | 21 | Tanner Rattlers | 48 |
| McAdory Yellow Jackets | 21 | Pinson Valley Indians | 24 |
| Minor Tigers | 19 | Gardendale | 27 |
| Montgomery Catholic Prep | 33 | Holtville | 14 |
| Moody Blue Devils | 42 | Walter Wellborn Panthers | 38 |
| Muscle Shoals Trojans | 49 | Pearl Cohn High | 20 |
| New Hope Indians | 42 | Elkmont Red Devils | 16 |
| Oakman | 14 | Cordova Blue Devils | 28 |
| Pelham | 27 | Northridge Jaguars | 41 |
| Phil Campbell Bobcats | 45 | Phillips Bear Creek Bears | 62 |
| Plainview Bears | 26 | Section Lions | 0 |
| Pleasant Valley Raiders | 6 | White Plains Wildcats | 18 |
| Priceville Bulldogs | 36 | Danville Hawks | 14 |
| Ragland Purple Devils | 26 | Cedar Bluff Tigers | 28 |
| Randolph County | 13 | Westbrook Warriors | 10 |
| Red Bay Tigers | 35 | Belmont | 0 |
| Saint John Paul | 21 | D.A.R. | 47 |
| Saks Wildcats | 47 | Weaver Bearcats | 21 |
| Scottsboro Wildcats | 30 | North Jackson Chiefs | 28 |
| Shoals Christian Flame | 36 | Berry Wildcats | 68 |
| South Lamar Stallions | 56 | Holy Spirit | 0 |
| Sparkman Senators | 39 | Russellville Golden Tigers | 36 |
| Springville Tigers | 13 | Talledega | 12 |
| St. Clair County | 9 | Southside Panthers | 24 |
| Stanhope Elmore | 28 | Benjamin Russell | 48 |
| Sumiton Christian Eagles | 51 | Lynn Bears | 14 |
| Susan Moore Bulldogs | 14 | Oneonta Redskins | 28 |
| Sylacauga | 42 | Childersburg | 18 |
| Sylvania Rams | 0 | Fyffe Red Devils | 34 |
| Talladega Central | 32 | Spring Garden Panthers | 14 |
| Tallassee | 28 | Dadeville | 22 |
| Tarrant | 6 | Ramsay | 50 |
| Tharptown Wildcats | 0 | Decatur Heritage | 27 |
| Tuscaloosa County Wildcats | 35 | Hillcrest Tuscaloosa Patriots | 7 |
| Vestavia Hills | 17 | Oxford | 10 |
| Victory Christian Lions | 50 | Woodville Panthers | 14 |
| Vina Red Devils | 6 | Meek Tigers | 30 |
| Vinemont Eagles | 7 | Cold Springs | 50 |
| Walker Vikings | 28 | Madison Academy Mustangs | 6 |
| Waterloo Cougars | 13 | Mars Hill | 48 |
| West End Patriots | 71 | Coosa Christian Conquerors | 0 |
| West Point Warriors | 49 | Hanceville Bulldogs | 0 |
| Westminster Christian Wildcats | 10 | Randolph Raiders | 13 |
| Winterboro | 20 | Thorsby | 8 |
| Woodland Bobcats | 14 | Loachapoka | 26 |
| Woodlawn | 6 | Carver | 26 |